A public-service announcement from the American Cancer Society featuring Mr. Magoo. Not part of the regular series, this rare cartoon begins with a bunch of clips talking about the history of the movies, then has some discussion about how Magoo is made, and a talk with Jim Backus. Then the bulk of the film is a Mr. Magoo cartoon featuring Magoo learning about cancer danger signs and how to protect yourself.

Magoo mistakes three bear cubs for three scouts.

The near-sighted one decides to take a hunting-and-fishing trip, and hires a Native American guide. He quickly grows impatient with the guide and takes over leading the way. He winds up in a big city and in a park lake, trail-blazing his way over park benches, statutes and through the zoo, releasing a lion along the way.

The title of this short is a play on the title of the feature film Destination Moon (which itself has an animated sequence made by Walter Lantz and starring Woody Woodpecker) and once again Magoo and his myopia take an adventure, hand in hand, off to the "Moon". The life that man leads!

Expecting a visit from his practical joker friend Smiley, Mr. Magoo instead entertains an escaped mental patient.

Foreign-flavored intrigue abounds when Mr. Magoo is mistaken for a fellow spy aboard a European train.

Magoo and Waldo are on safari in Africa.

Magoo obliviously foils a criminal’s robbery plans.

The near-sighted Mr. Magoo, further lost than usual, mistakes a bullring in Mexico for a highway in the United States, and his myopic wanderings through the arena cause much havoc, and draws very few cheers, especially from the bull.

Magoo thinks he’s entering a talent show but ends up at a dentist.